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. 2016 Dec 1;10:3933–3946. doi: 10.2147/DDDT.S116286

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© 2016 Lv et al. This work is published and licensed by Dove Medical Press Limited

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Accumulative release of 6MP from MSNS-6MP.

Notes: (A) GSH promoted accumulative release profiles of 6MP from MSNS-6MP in pH 7.4 PBS; (B) DTT promoted accumulative release profiles of 6MP from MSNS-6MP in pH 7.4 PBS; (C) the accumulative release profiles of 6MP from MSNS-6MP in rat serum.

Abbreviations: 6MP, 6-mercaptopurine; MSNS, SH surfaced mesoporous silica nanoparticles; GSH, glutathione; PBS, phosphate buffered saline; DTT, dithiolthreitol; MSNS-6MP, 6MP surfaced MSNS.