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. 2016 Dec 1;10:3933–3946. doi: 10.2147/DDDT.S116286

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© 2016 Lv et al. This work is published and licensed by Dove Medical Press Limited

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Serum ALT, AST and Cr levels of the mice treated with CMCNa, CDDP, CDDP plus 6MP and MSNS-6MP/CDDP.

Note: (A) serum ALT and AST of the S180 mice treated by CMCNa, CDDP plus 6MP, CDDP and MSNS-6MP/CDDP; (B) serum Cr of the S180 mice treated by CMCNa, CDDP plus 6MP, CDDP and MSNS-6MP/CDDP.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; Cr, creatinine; CMCNa, sodium carboxyl methyl cellulose; CDDP, cisplatin; 6MP, 6-mercaptopurine; MSNS, SH surfaced mesoporous silica nanoparticles; MSNS-6MP, 6MP covalently modified MSNS; MSNS-6MP/CDDP, CDDP-loaded MSNS-6MP.