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. 2016 Dec 1;9:7297–7307. doi: 10.2147/OTT.S111291

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© 2016 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Upregulation of miR-1247 expression impairs cell proliferation and invasion in non-small-cell lung cancer.

Notes: (A) qRT-PCR assay detected the miR-1247 level in A549 and H1299 cells with miR-1247 overexpression. MTT analysis of cell proliferation in A549 cells (B) and in H1299 cells (C) treated with miR-1247 mimics/mimicsNC/5-Aza. (D) Cell proliferation ability was used to detect cell proliferation in A549 and H1299 cells with miR-1247 overexpression or exposure to 5-Aza. (E) Transwell migration assay with miR-1247 overexpression or exposure to 5-Aza. Bars represent mean values ± standard deviation. ***P<0.001; **P<0.01; *P<0.05, N=3.

Abbreviations: qRT-PCR, quantitative real-time polymerase chain reaction; h, hours; OD, optical density; Con, control.