Figure 5.

MiR-1247 inhibited the effects of STMN1 that accelerated cell invasion and cell cycle.

Notes: (A) STMN1 protein expression was analyzed by Western blot. A549 and H1299 cells were co-transfected with pre-miR-1247 and pCDNA3.1-STMN1. (B) Increased miR-1247 expression reversed STMN1-induced cell invasion. (C) Overexpression of miR-1247 reversed STMN1-induced cell cycle progression at the G1/S phase in A549 and H1299 cells. Bars represent mean values ± standard deviation. ***P<0.001; **P<0.01; *P<0.05, N=3.

Abbreviation: NC, cells transfected with mimics NC and pcDNA3.1.