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. 2016 Nov 30;9:169–177. doi: 10.2147/TACG.S122250

Table 3.

Correlation between true* and estimated SNP effects under four simulation scenarios using noise data analyzed with threshold models either ignoring (M2) or contemplating (M3) misclassification

Model 5% and 0%
7% and 3%
Moderate** Extreme Moderate Extreme
M2 0.894 0.777 0.807 0.675
M3 0.969 0.911 0.907 0.892

Notes:

*

True effects were calculated based on analysis of the true data (M1).

**

Moderate effects for influential SNPs. M1: true data analyzed with a standard model. M2: noisy data analyzed with threshold model ignoring misclassification. M3: noisy data analyzed with threshold model contemplating misclassification (proposed method).

Abbreviation: SNP, single nucleotide polymorphism.