Fig. 3.
Hypothetical model of TMM selection and therapeutic targeting during metastasis. The top row (blue box) depicts the dissemination of a telomerase-positive cancer cell from the primary tumor site to a distant organ, while the bottom row (pink box) depicts these same events in an ALT-positive cell. See Section 5. “Telomere homeostasis: Determinant or consequence of metastatic progression?” for details.