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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: J Comp Neurol. 2016 Aug 11;525(2):271–290. doi: 10.1002/cne.24059

Figure 11. Comparison chartings of citric acid-evoked c-Fos-like Immunoreactivity (Fos-LI) within the brainstem of ‘Control’ (P2X WT) (Left side of each pair) and ‘Taste Blind’ (P2X-dbl KO) (Right side of each charting pair) mice.

Figure 11

Across all nTS levels, Fos-LI (green circles) is significantly reduced in the nTS of P2X-dbl KO mice compared to WT. In contrast, in non-nTS areas displaying high levels of CGRP-immunoreactivity (magenta fibers), including the dorsomedial trigeminal nucleus (DMSp5), spinal trigeminal tract (SP5), and the nucleus Ambiguus (Nuc. Amb.), Fos-LI density is similar between P2X WT and P2X-dblKO mice.