Table 1.
Markers for Treg cell subsets.
| Treg cell subsets | ||||
|---|---|---|---|---|
| Origin subsets |
Functional subsets |
|||
| Thymus-derived Treg | Peripherally derived Treg | Resting Treg | Effector Treg | Tissue-resident Treg |
| Cytotoxic T lymphocyte antigen (CTLA4) | CTLA4 | CTLA4low | CTLA4hi | Adipose tissue-resident Treg |
| GITR | GITR | CD62Lhi | CD62Llow | PPARGγhi, Foxp3hi |
| CD103 | CD103 | CD45RAhi | CD45RAlow | |
| Helios | CD25hi | CD25hi | CD44hi | |
| Neuropilin-1 | CD127low | CD127low | KLRG1+ CD103+ | Skeletal muscle-resident Treg |
| TIGIT | Foxp3hi | CCR7hi | CD25hi | Tbethi, Foxp3hi, CXCR3hi |
| FCRL3 | CD127low | |||
| CD25hi | Foxp3hi | |||
| CD127low | CCR7low | |||
| Foxp3hi | CTLA4hi | |||