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. 2016 Dec 6;10:611. doi: 10.3389/fnhum.2016.00611

Table 1A.

Sample characteristics.

Subject Gender Age at surgery (year) Disease duration at surgery (year) LEDD pre-DBS (mg) UPDRS pre-DBS meds-off (score) UPDRS pre-DBS meds-on (score) LEDD post-DBS (mg) UPDRS post-DBS meds-off, stim-on (score)
wue2* male 65 10 1100 40 23 800 19
wue3 male 61 18 2725 40 9 600 13
wue5* male 67 17 1050 49 24 500 13
wue6 male 51 11 1133 47 12 180 9
wue7 male 61 10 650 43 24 220 19
wue9* male 55 19 1200 50 11 730 16
wue11* female 53 11 1300 55 4 460 9

Demographic and clinical information. Before surgery participants were tested after overnight withdrawal of all dopaminergic medications (meds-off). To evaluate the effect of levodopa (meds-on), the patient had turned into a good quality “on-state” upon receiving 1–1.5-times the levodopa-equivalent of the preoperative morning dose. After surgery, all patients were evaluated in meds-off condition but under chronically effective STN stimulation (meds-off, stim-on). *Indicates the four patients (i.e., wue2, 5, 9 and 11) who were able to complete the motor task (i.e., with both hands in the required amount of time, please refer to “Task and Experimental Design” in the “Materials and Methods Section”). DBS, deep brain stimulation; LEDD, levodopa equivalent daily dose; STN, subthalamic nucleus; UPDRS-III, Unified Parkinson Disease Rating Scale motor part.