Table 3.

Criteria defining resectability status according to NCCN Guidelines version 1.2016 (Pancreatic adenocarcinoma)

Resectability status	Distant metastases	Arterial	Venous
Resectable	No	No arterial tumor contact [celiac axis (CA), superior mesenteric artery (SMA) or common hepatic artery (CHA)]	No tumor contact with the superior mesenteric vein (SMV) or portal vein (PV) or ≤180° contact without vein contour irregularity
Boderline resectable	No	Head/uncinated process: Solid tumor contact with CHA without extension to CA or hepatic artery bifurcation allowing for safe and complete resection and reconstruction Solid tumor contact with the SMA of ≤180° Body and tail: Solid tumor contact with the CA of ≤180° Solid tumor contact with the CA of >180° without involvement of the aorta and with intact and uninvolved gastroduodenal artery	Solid tumor contact with the SMV or PV of >180°, contact of ≤180° with contour irregularity of the vein or thrombosis of the vein but with suitable vessel proximal and distal to the site of involvement allowing for safe and complete resection and vein reconstruction Solid tumor contact with the inferior vena cava (IVC)
Unresectable	Yes (including non-regional lymph node metastasis)	Head/uncinated process: Solid tumor contact with SMA >180° Solid tumor contact with CA >180° Solid tumor contact with the first jejunal SMA branch Body and tail: Solid tumor contact of >180° with de SMA or CA Solid tumor contact with the CA and aortic involvement	Head/uncinated process: Unreconstructible SMV/PV due to tumor involvement or occlusion (can be due tumor or bland thrombus) Contact with most proximal draining jejunal branch into SMV Body and tail: Unreconstructible SMV/PV due to tumor involvement or occlusion (can be due tumor or bland thrombus)