Table 5.
Methods to preserve fertility in females with cancer
| Methods | ¿Need ovarian stimulation? | ¿Delay cancer treatment? | ¿Need male partner or sperm donor? | Success rates | Special considerations |
|---|---|---|---|---|---|
| GnRHa | No | No | No | Controversial, just partially recommended in ER-negative breast cancer patient | |
| Embryo freezing | Yes | Yes | Yes | Cumulative pregnancy rate of 66% among women with cancer | |
| Oocyte cryopreservation | Yes | Yes | No | Pregnancy rate per cycle of 50.2% or per embryo transfer 55.4% | |
| Immature oocyte cryopreservation | No | No | No | ||
| Ovarian tissue cryopreservation | No | No | No | Pregnancy rate of 25% among women with cancer | No indication when high risk of ovarian metastases |