Table 1.
Physiological responses to sustained exposure to hypobaric hypoxia in different native populations (in comparison to values seen at sea level) [29, 46, 47].
Adapted from [33]
| Phenotype | Andean | Tibetan | Ethiopian |
|---|---|---|---|
| Resting ventilation | No increase | 50% higher | Not reported |
| Hypoxic ventilatory response | Blunted (low) | Similar to sea level (high) | Not reported |
| Arterial oxygen saturation | Elevated | No increase | Elevated |
| Hemoglobin concentration | Elevated | No increase (up to 4000 m) | No increase (up to 4000 m) |
| Pulmonary arterial pressure | Elevated | Minimal increase | Elevated |
| Nitric oxide levels | Elevated | Markedly elevated | Not reported |
| Birth weight | Elevated | Elevated | Not reported |
| CMS incidence | Frequent | Rare | Very rare |