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. 2016 Nov 28;18(12):1237–1242. doi: 10.1007/s12094-016-1583-0

Table 2.

Prophylactic antiemetic treatment with high emetogenic potential

Day 1 Day 2 Day 3 Day 4
Option A
 5HT-3 receptor antagonista
 Dexamethasone 12 mg PO/IV Dexamethasone 8 mg PO/IV daily Dexamethasone 8 mg PO/IV daily Dexamethasone 8 mg PO/IV daily
 Aprepitant or Fosaprepitant Aprepitant Aprepitant
Option B
 NEPA = Netupitant 300 mg/palonosetron 0.5 mg PO
 Dexamethasone 12 mg PO/IV Dexamethasone 8 mg PO/IV daily Dexamethasone 8 mg PO/IV daily Dexamethasone 8 mg PO/IV daily
Option C
 Olanzapine 10 mg PO Olanzapine 10 mg PO daily Olanzapine 10 mg PO daily Olanzapine 10 mg PO daily
 Palonosetron 0.25 mg IV
 Dexamethasone 20 mg PO/IV

aPalonosetron is advised because of its superiority in controlling delayed emesis