Table 2.
Day 1 | Day 2 | Day 3 | Day 4 |
---|---|---|---|
Option A | |||
5HT-3 receptor antagonista | |||
Dexamethasone 12 mg PO/IV | Dexamethasone 8 mg PO/IV daily | Dexamethasone 8 mg PO/IV daily | Dexamethasone 8 mg PO/IV daily |
Aprepitant or Fosaprepitant | Aprepitant | Aprepitant | |
Option B | |||
NEPA = Netupitant 300 mg/palonosetron 0.5 mg PO | |||
Dexamethasone 12 mg PO/IV | Dexamethasone 8 mg PO/IV daily | Dexamethasone 8 mg PO/IV daily | Dexamethasone 8 mg PO/IV daily |
Option C | |||
Olanzapine 10 mg PO | Olanzapine 10 mg PO daily | Olanzapine 10 mg PO daily | Olanzapine 10 mg PO daily |
Palonosetron 0.25 mg IV | |||
Dexamethasone 20 mg PO/IV |
aPalonosetron is advised because of its superiority in controlling delayed emesis