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. 2016 Oct 28;468(11):1995–2006. doi: 10.1007/s00424-016-1892-8

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — NF regulation of myofilament Ca²⁺ sensitivity. a Simultaneous recordings of LV myocyte sarcomere shortening/relengthening and intracellular Ca²⁺ transients in NT and in NF. b Phase-plane loop of sarcomere shortening/relengthening vs. [Ca²⁺]_i transient. The relaxation phase of the loop shifted to the right in NF compared to that in NT. Ca²⁺ concentration at 50 % sarcomere relengthening (EC₅₀) was significantly larger in NF