Table 1.

Model parameters for simulation of the effects of NF on membrane currents and sarcoplasmic reticulum function

Parameter	Unit	Description	NT	NF
gCaL	nS	Maximum conductance for ICaL	31.000	29.512
Vh,act,CaL	mV	Half-activation voltage for ICaL	−15.3	−17.1
kact,CaL	mV	Slope factor of activation for ICaL	5.0	4.8
Vh,inact,CaL	mV	Half-inactivation voltage for ICaL	−26.7	−27.4
SFtau,inact,CaL	–	Scaling factor for inactivation τ of ICaL	1.00	1.04
gto	nS	Maximum conductance of Ito	569.2575	512.3318
kNaCa	mM−4	Scaling factor for INaCa	9.984·10−3	9.584·10−3
ν1	ms−1	Maximum RyR (ryanodine) channel Ca2+ flux	1.800	1.656
KSR	–	Scaling factor for Ca2+-ATPase	1.00	0.92
$K_{\text{htrpn}}^{+}$	mM−1 s−1	Ca2+ on rate for troponin high-affinity sites	200	20
$K_{\text{ltrpn}}^{+}$	mM−1 s−1	Ca2+ on rate for troponin low-affinity sites	40	4

See glossary of Pandit’s model [17] for detailed explanation. All other model parameters are the same as those of endocardial myocyte in the Pandit’s model.