Table 2.
Simple regression analysis.
Cathepsin S | Cystatin C | Cat S/Cys C (/103) | ||||
---|---|---|---|---|---|---|
R | p | R | p | R | p | |
Age | 0.033 | 0.72 | 0.226 | 0.01∗ | −0.128 | 0.16 |
Pack-Year | 0.099 | 0.27 | 0.096 | 0.29 | −0.001 | 0.99 |
BMI | 0.175 | 0.052 | −0.042 | 0.65 | 0.132 | 0.14 |
Serum Cr | 0.164 | 0.07 | 0.266 | 0.003∗∗ | −0.093 | 0.30 |
% VC | −0.0004 | 0.997 | −0.054 | 0.55 | 0.076 | 0.40 |
FEV1/FVC | 0.261 | 0.003∗∗ | −0.014 | 0.88 | 0.242 | 0.007∗∗ |
% FEV1 predicted | 0.179 | 0.045∗ | −0.020 | 0.83 | 0.188 | 0.04∗ |
PEF | 0.083 | 0.36 | −0.1664 | 0.07 | 0.199 | 0.03∗ |
V 50 | 0.131 | 0.15 | −0.110 | 0.23 | 0.187 | 0.04∗ |
% DLCO predicted | 0.089 | 0.37 | −0.251 | 0.01∗ | 0.277 | 0.005∗∗ |
% DLCO/V A | 0.197 | 0.046∗ | −0.120 | 0.23 | 0.244 | 0.01∗ |
LAA | −0.228 | 0.01∗ | 0.033 | 0.71 | −0.233 | 0.009∗∗ |
mPA | 0.112 | 0.24 | 0.139 | 0.14 | −0.054 | 0.58 |
abAo | 0.181 | 0.06 | 0.267 | 0.005∗∗ | 0.045 | 0.64 |
Current/Ex (51/74) | 24.8/22.8 | 0.17 | 2.78/2.65 | 0.44 | 9.77/9.42 | 0.65 |
HT (+/−) (22/103) | 24.5/23.4 | 0.57 | 2.74/2.70 | 0.57 | 9.68/9.54 | 0.85 |
ICS (+/−) (17/108) | 20.1/24.2 | 0.06 | 2.59/2.72 | 0.59 | 8.36/9.75 | 0.21 |
M/F (116/9) | 23.7/23.4 | 0.93 | 2.66/3.32 | 0.04∗ | 9.69/7.90 | 0.22 |
∗ p < 0.05; ∗∗ p < 0.01. Cat: cathepsin; Cys: cystatin; BMI: body mass index; Cr: creatinine; VC: vital capacity; FEV1/FVC: ratio of forced expiratory volume in 1 second to forced vital capacity; FEV1: forced expiratory volume in 1 second; PEF: peak expiratory flow rate; V 50: the air flow rate at 50% vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; DLCO/V A: diffusing capacity of the lung for carbon monoxide divided by the alveolar volume; LAA: low attenuation area; mPA: main pulmonary artery; abAo: abdominal aorta; Ex: ex-smoker; HT: hypertension; ICS: inhaled corticosteroid; M: male; F: female.