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Effect of haloperidol (1.6–12.8 μg/mL) on the pEC50 and % maximal contraction (% Emax) of dopamine-induced contractions of isolated rat vas deferens.
| Treatment | pEC50 | % Emax |
|---|---|---|
| DMSO (0.001%) | 1.31 ± 0.04 | 21.94 ± 2.93 |
| HAL (1.6 μg/mL) | 1.32 ± 0.04 | 19.87 ± 2.71 |
| HAL (3.2 (μg/mL) | 1.37 ± 0.03 | 18.17 ± 2.43 |
| HAL (6.4 μg/mL) | 1.42 ± 0.04 | 14.15 ± 1.88 |
| HAL (12.8 μg/mL) | 1.53 ± 0.07 | 10.32 ± 1.30∗ |
∗p < 0.05 when compared with DMSO (0.001%).
