Table 1.
Characteristics of liver transplant candidates before propensity score matching by transplant type (UNOS data between 2003 and 2013 in the USA)
| N | LTA | SLK | P value | |
|---|---|---|---|---|
| N = 35,947 | 34,337 | 1610 | ||
| Age (yr)a | 35,947 | 52.6 ± 10 | 54.3 ± 9.6 | <0.001 |
| Gender (female, %)a | 35,947 | 33.9 | 34.1 | 0.84 |
| Race (AA, %)a | 35,947 | 8.9 | 15.3 | <0.001 |
| Recipient DM (%)a | 35,947 | 23.5 | 37 | <0.001 |
| Liver disease (%)a | 35,947 | <0.001 | ||
| HCV infection | 27.8 | 28.6 | ||
| ETOH and NASH | 23.6 | 23.4 | ||
| Cholestatic | 10.9 | 7 | ||
| Others | 37.6 | 40.1 | ||
| BMIa | 35,919 | 28.3 ± 5.8 | 27.4 ± 5.8 | <0.001 |
| Scr (mg/dl) at transplant (if not on dialysis)a | 34,403 | 1.5 ± 1 | 3 ± 1.2 | <0.001 |
| eGFR at transplant (ml/min per 1.73 m2)b | 34,403 | 62.9 ± 32.5 | 26.9 ± 17.2 | <0.001 |
| INR at transplanta | 35,947 | 2 ± 1.2 | 1.9 ± 0.9 | <0.001 |
| Total bilirubin (mg/dl) at transplanta | 34,258 | 10.7 ± 12 | 12.4 ± 14.5 | <0.001 |
| On dialysis at transplant (%) | 35,947 | 8.6 | 50 | <0.001 |
| MELD at transplant | 35,944 | 24.2 ± 9.2 | 30.9 ± 8.4 | <0.001 |
| Liver DRIa | 30,982 | 1.4 ± 0.4 | 1.2 ± 0.3 | <0.001 |
| Median time to transplant (25th and 75th percentiles), moa | 35,946 | 1.9 (0.4, 6.8) | 1.3 (0.4, 5.2) | 0.001 |
± Denotes 1 SD.
AA, African American; BMI, body mass index; DM, diabetes; DRI, donor risk index; eGFR, estimated glomerular filtration rate; ETOH and NASH, alcohol and nonalcoholic steatohepatitis; HCV, hepatitis C virus; INR, international normalized ratio; LTA, liver transplant alone; MDRD, Modification of Diet in Renal Disease Study; MELD, model for end-stage liver disease; N, sample size; Scr, serum creatinine; SLK, simultaneous liver-kidney transplantation; UNOS, United Network for Organ Sharing.
The variables used in the propensity score matching.
The MDRD 4-variable equation to eGFR, calculated for the recipient who was not on dialysis.