Table 2.
Causes (reported for liver transplant recipients) and observed frequencies of death and posttransplant outcomes after the propensity score matching
| Liver transplant recipients not on dialysis either at listing or transplant, and Scr < 2 mg/dl at transplant (LK1) |
Liver transplant recipients not on dialysis either at listing or transplant, and Scr ≥ 2 mg/dl at transplant (LK2) |
Liver transplant recipients not on dialysis at listing but on dialysis at transplant (LK3) |
Liver transplant recipient on dialysis both at listing and transplant (LK4) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LTA | SLK | P | LTA | SLK | P | LTA | SLK | P | LTA | SLK | P | |
| N | 536 | 144 | 1237 | 570 | 579 | 383 | 348 | 264 | ||||
| Posttransplant mortality | ||||||||||||
| Incidence rate per patient-year (%) | 5.7 | 4.7 | 7.6 | 5.7 | 9.2 | 7.4 | 10 | 8.4 | ||||
| Incidence rate ratio (95% CI) | 0.81 (0.50–1.28) | 0.38 | 0.75 (0.60–0.92) | 0.005 | 0.81 (0.61–1.05) | 0.10 | 0.84 (0.61–1.16) | 0.28 | ||||
| Time to death (mo) | 31 ± 32 | 19 ± 20 | 0.08 | 27 ± 30 | 30 ± 32 | 0.33 | 19 ± 27 | 24 ± 31 | 0.19 | 16 ± 11 | 16 ± 10 | 0.99 |
| Causes of death reported for liver transplantation (%) | 0.09∗ | 0.09∗ | 0.10∗ | 0.06∗ | ||||||||
| Graft failure | 14.4 | 11.1 | 13 | 11.1 | 9.4 | 13.1 | 12.5 | 7.4 | ||||
| CVS | 13.6 | 14.8 | 18.6 | 17.1 | 22.7 | 16.7 | 17.9 | 7.4 | ||||
| Hemorrhage | 6.8 | 0 | 5.1 | 0.9 | 4.7 | 0.0 | 6.3 | 5.9 | ||||
| Infection | 14.4 | 33.3 | 21.5 | 25.6 | 31.3 | 27.4 | 23.2 | 41.2 | ||||
| Malignancy | 14.4 | 11.1 | 9.8 | 9.4 | 7.8 | 7.2 | 9.8 | 8.8 | ||||
| Renal failure | 5.1 | 14.8 | 9.5 | 4.3 | 7 | 3.6 | 11.6 | 4.4 | ||||
| Other | 14.4 | 11.1 | 8.8 | 16.3 | 8.6 | 13.1 | 12.5 | 11.8 | ||||
| Unknown | 17 | 3.7 | 13.7 | 15.4 | 8.6 | 19.1 | 6.3 | 13.4 | ||||
| Posttransplant ESRD | ||||||||||||
| Incidence rate per 1000 patient-days | 1.1 | 1.5 | 1.3 | 0.8 | 1.4 | 1.7 | 2.6 | 0.9 | ||||
| Incidence rate ratio | 1.36 (0.62–2.79) | 0.38 | 0.63 (0.43–0.89) | 0.01 | 1.22 (0.74–2.00) | 0.40 | 0.34 (0.16–0.69) | 0.001 | ||||
| Kidney transplantation post-LTA or post-SLK, n (%) | 6 (1.1) | 3 (2.1) | 0.37 | 36 (2.9) | 5 (0.9) | 0.01 | 18 (3.1) | 6 (1.6) | 0.13 | 11 (3.2) | 7 (2.6) | 0.71 |
| Liver retransplantation | 20 (3.7) | 4 (2.8) | 0.58 | 50 (4) | 14 (2.5) | 0.09 | 23 (4) | 11 (2.9) | 0.37 | 10 (2.9) | 8 (3) | 0.91 |
CI, confidence interval; CVS, cardiovascular system; ESRD, end-stage renal disease; LTA, liver transplant alone; Scr, serum creatinine; SLK, simultaneous liver-kidney transplantation.
∗
P value for trend (type III P value).