Table 3.
Cox proportional hazard models for mortality among patients undergoing simultaneous liver-kidney transplant versus liver transplant alone by strata defined by renal function and dialysis status
| Model | Liver transplant recipients not on dialysis either at listing or transplant, and Scr < 2 mg/dl at transplant (LK1) |
Liver transplant recipients not on dialysis either at listing or transplant, and Scr ≥ 2 mg/dl at transplant (LK2) |
Liver transplant recipients not on dialysis at listing but on dialysis at transplant (LK3) |
Liver transplant recipient on dialysis both at listing and transplant (LK4) |
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|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Before propensity score matching | ||||||||
| Missing data, % (missing/total N) | 0.9 (234/26,209) | 1.4 (82/5971) | 2.5 (63/2551) | 1.5 (18/1216) | ||||
| Unadjusted model | 0.83 (0.56–1.22) | 0.34 | 0.83 (0.70–0.99) | 0.04 | 0.92 (0.76–1.13) | 0.42 | 1.04 (0.82–1.32) | 0.73 |
| After propensity score matching | ||||||||
| Missing data, % (missing/total N) | 0.4 (3/680) | 1.5 (27/1807) | 2.1 (20/962) | 2.1 (13/612) | ||||
| Model adjusted for other covariatesa | 0.88 (0.56–1.39) | 0.59 | 0.77 (0.62–0.96) | 0.02 | 0.89 (0.68–1.16) | 0.39 | 0.89 (0.64–1.23) | 0.48 |
CI, confidence interval; HR, hazard ratio; N, sample size; Scr, serum creatinine.
Other covariates: ABO type, encephalopathy category, ascites category, estimated slope of creatinine from wait-listing to transplantation (for the LK1 and LK2 groups), hospitalized to ICU before transplant (on mechanical ventilation), and transplant year.