Table 1. Characteristics of the rs179247A/G polymorphism allelic and genotype distribution for GD risk in studies included in the meta-analysis.
Authors[ref.] | Year | Ethnicity | Methods | HWE | Total/Genotypes(AA/AG/GG) | A allele frequency(%) | OR(95% CI) | ||
Cases | Controls | Cases | Controls | ||||||
Oliver J. Brand et al | 2009 | European | Taq man | 0.454 | 768 (279 /359 /100) | 768 (182/ 322 / 160) | 46.0 | 38.0 | 1.54 (1.32–1.78) |
Rafał Płoski et al | 2010 | European Set 1 | Taq man | 0.443 | 558 (139 / 270 /149) | 520 (81 / 259 / 180) | 49.1 | 40.5 | 1.42 (1.20–1.68) |
Rafał Płoski et al | 2010 | European Set 2 | Taq man | 0.857 | 196 (58 / 84 / 54) | 198 (34 / 98 / 67) | 51.0 | 41.7 | 1.46 (1.10–1.93) |
Rafał Płoski et al | 2010 | European Set 3 | Taq man | 0.393 | 2504 (879 /1110 / 351) | 2784 (737 /1243 / 561) | 61.3 | 53.5 | 1.38 (1.27–1.49) |
Shaoying Yang et al | 2011 | Asian | Taq man | 0.471 | 1066 (564/427/75) | 1107 (486/503/118) | 72.9 | 66.6 | 1.35 (1.19-1.54) |
Lin Liu et al | 2012 | Asian | MALDI-TOFMS | 0.504 | 404 (230/140/24) | 242 (120/88/20) | 76.14 | 71.93 | 1.25 (0.96-1.62) |
Ran Wang et al | 2012 | Asian | Taq man | 0.859 | 618 (353/220/45) | 646 (260/298/88) | 74.92 | 63.31 | 1.73 (1.46-2.05) |
Haili Wang et al | 2013 | Asian | Taq man | 0.713 | 471 (258/174/38) | 472 ( 216/204/52) | 73.4 | 67.4 | 1.34 (1.10-1.63) |
N. Inoue1 et al | 2013 | Asian | PCR-RFLP | 0.066 | 112 (57/44/11) | 56 (18/33/5) | 70.5 | 61.6 | 1.49 (0.93-1.50) |
N. E. Bufalo et al | 2015 | South America | Taq man | 0.213 | 279 (117/138/24) | 296 (92/154/50) | 66.7 | 57.1 | 2.82 (1.56–4.99) |