Table 2. Characteristics of the rs12101255T/C polymorphism allelic and genotype distribution for GD risk in studies included in the meta-analysis.
| Authors[ref.] | Year | Ethnicity | Methods | HWE | Total/Genotypes(TT /TC/ CC) | T allele frequency(%) | OR(95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | ||||||
| Oliver J. Brand et al | 2009 | European | Taq man | 0.964 | 768 (150/345 /197) | 768 (89/ 295 / 268) | 35.0 | 28.0 | 1.55( 1.33–1.81) |
| Rafał Płoski et al | 2010(1) | European Set 1 | Taq man | 0.473 | 558 (75 /245 /238) | 520 (35 / 212 / 273) | 35.4 | 27.1 | 1.47( 1.23–1.77) |
| Rafał Płoski et al | 2010(2) | European Set 2 | Taq man | 0.261 | 196 (32 /94 /70) | 198 (17 /71 /110) | 40.3 | 26.5 | 1.87( 1.39–2.53) |
| Rafał Płoski et al | 2010(3) | European Set 3 | Taq man | 0.412 | 2504 (482/1136 / 687) | 2784 (338/1148 / 1046) | 45.6 | 36.0 | 1.49( 1.37–1.61) |
| Lin Liu et al | 2012 | Asian | MALDI-TOFMS | 0.550 | 404 (187/179/38) | 242 (86/119/35) | 68.44 | 60.63 | 1.41(1.11-1.78) |