Figure 5. BC-DETC treatment modulates the cellular recall response.

Mice were infected and three weeks later BC-DETC (at 350 μg/cm²) was applied for three weeks. Controls received empty BC. Draining lymph nodes were re-stimulated in vitro and cytokines were quantified by ELISA. (A) Heat map depicting cytokine production, colored to indicate levels. Insert shows data for individual mice at six weeks. (B) Cytokine levels detected in culture supernatants, at six weeks. Data are from a representative experiment performed with six mice per group. *p < 0.05.