Figure 4. Expression of ERβ in SAT from 3- and 12-month-old male and female mice.

(A) Expression of ERβ in the nuclei of SAT in young and aged male WT mice was similar (a,c). Expression of ERβ in the nuclei of SAT in 3- and 12-month-old female WT mice was higher than in age-matched male mice (b,d). (B) Quantification of ERβ. Higher expression of ERβ was observed in female SAT than in male SAT. **p < 0.01, ***p < 0.001, female vs. male. All pictures are 40x magnification.