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. 2016 Dec 6;6:38579. doi: 10.1038/srep38579

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Copyright © 2016, The Author(s)

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(A) Treatment with LY3201 induced more multilocular lipid droplets as indicated by H&E staining (red arrow) (a,c) and expression of UCP1 (red arrow) (b,d). All pictures were 20x magnification. (B) LY3201 did not affect ovary or uterus morphology in female ERα^−/− mice. As expected there were many hemorrhagic cystic follicles (HC) and lack of mature follicles and corpora lutea in ERα^−/−mice. ERα^−/− mice uterus was also hypoplastic with thinner epithelial layer (b,d). However, treatment with LY3201 did not further change the morphology of ovaries (a,c) or uterus (b,d). E: Epithelial layer, L: lumen of the organ. Pictures of ovaries are 10x magnification. Pictures of uterus are 20x magnification.