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. 2016 Dec 6;6:38128. doi: 10.1038/srep38128

Table 1. IC50 values of benzo[h]quinolines(3a-3j) for the growth of G361, H460, MCF7 and HCT116 cells.

Compound IC50 (μM)
G361 H460 MCF7 HCT116
3a 42.3 (±0.1) 9.5 (±0.03) 7.5 (±1.3) 9.6 (±0.9)
3b 34.8 (±1.1) 8.2 (±2.0) 11 (±2) 7.6 (±1.1)
3c 29.2 (±1.1) 8.4 (±0.2) 10.9 (±0.7) 10.7 (±1)
3d 7.4 (±0.2) 7.0 (±1.2) (9.7±0.7) 7.2 (±1.6)
3e 5.3 (±1.7) 6.8 (±0.7) 7.6 (±1.2) 6.8 (±0.2)
3f 7.4 (±0.5) 5.4 (±0.6) 4.7 (±0.9) 4.9 (±0.2)
3g 14.5 (±2.4) 8.2 (±1.0) 6.8 (±1.5) 9.2 (±1.2)
3h 5.5 (±0.03) 5.4 (±0.4) 5.2 (±1) 7.2 (±0.2)
3i 19.1 (±0.05) 9.5 (±0.1) 8.9 (±0.4) 6.9 (±0.1)/
3j 7.4 (±0.3) 4.8 (±0.3) 5.2 (±1.2) 6.8 (±0.5)
Doxorubicin 2.1 (±0.4) 1.5 (±0.05) 2.4 (±0.8) 2.1 (±0.5)