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. 2016 Dec 6;6:38178. doi: 10.1038/srep38178

Table 2. Overview of GMine analysis tabs.

Method Description
Upload Data upload
Data Information on uploaded data
QViz Quantitative visualization of data as heatmap, barchart or bubble plots. Measurements are visualized for individual samples.
GroupPlots Comparison of measurements across multiple biological conditions (e.g. using ANOVA or non-parametric rank tests). Features that are significantly differentially distributed are presented as boxplots or barcharts.
Features Quantitative visualization of measurements obtained for individual features.
Stats Comparison of measurements across multiple biological conditions (e.g. using ANOVA, non-parametric rank tests, Bayesian ANOVA or DESeq2). P-values are adjusted for multiple testing and results are presented as table.
Multivariate Multivariate data analysis. Various methods are available for data ordination (e.g. PCA, PCoA, NMDS) and multivariate statistical testing (e.g. CCA, RDA).
Feat. Select Feature selection using stepwise regression, LASSO regression, random forest or LEfSe
Network Network analysis and clustering using self organizing maps
Biomarker Identification of biomarker candidates. Biomarkers are characterized by Area Under the Curve (AUC), fold change and delta (difference in mean in units of standard deviation). Results are presented as table and forest plot.
Regression Identification of associations between measurements and multiple explanatory variables using multivariable regression techniques
Rep. Measures Analysis of experimental data from repeated measures designs using mixed effect regression models. This technique can distinguish between group-specific effects and subject or cage-specific effects.
Paired Analysis of paired data using paired t-test or paired rank test
Norm Visualize the effect of different data transformation and data normalization methods
FactorAnalysis Factor analysis to reduce data dimensionality and remove redundant features