Table 3. Activation table of brain areas showing group differences during correct inhibition to lures; no differences were found between cirrhosis vs. no-cirrhosis and between amnestic group and unimpaired patients.
| Cluster Index | Z-score | MNI (mm) |
|||
|---|---|---|---|---|---|
| X | y | z | |||
| Amnestic/Non-amnestic >Unimpaireda | |||||
| Cluster 2: 2252 voxels | |||||
| Central Opercular Cortex, L | 2 | 3.50 | −42 | −22 | 20 |
| Postcentral Gyrus, L | 2 | 3.20 | −38 | −24 | 40 |
| Insular Cortex, L | 2 | 3.12 | −36 | −10 | 8 |
| Cluster 1: 1199 voxels | |||||
| Postcentral Gyrus, R | 1 | 3.16 | 34 | −32 | 40 |
| Posterior Cingulate Gyrus, R | 1 | 3.15 | 14 | −36 | 42 |
| Superior Parietal Lobule, R | 1 | 2.62 | 32 | −40 | 58 |
| Amnestic/Non-amnestic >Unimpairedb | |||||
| Cluster 4: 5395 voxels | |||||
| Temporal Occipital Fusiform Cortex, R | 4 | 3.63 | 38 | −60 | −10 |
| Occipital Pole, L | 4 | 3.54 | −22 | −102 | 4 |
| Occipital Pole, R | 4 | 3.40 | 32 | −90 | 30 |
| Cluster 3: 2670 voxels | |||||
| Central Opercular Cortex, L | 3 | 3.70 | −40 | −20 | 22 |
| Insular Cortex, L | 3 | 3.57 | −38 | −12 | 14 |
| Superior Parietal Lobule, L | 3 | 3.16 | −36 | −42 | 58 |
| Postcentral Gyrus, L | 3 | 3.02 | −58 | −14 | 46 |
| Cluster 2: 1585 voxels | |||||
| Parietal Operculum Cortex, R | 2 | 3.37 | 48 | −24 | 30 |
| Postcentral Gyrus, R | 2 | 3.35 | 56 | −18 | 40 |
| Cluster 1: 1029 voxels | |||||
| Precuneous Cortex, R | 1 | 3.25 | 14 | −36 | 44 |
| Precuneous Cortex, L | 1 | 3.20 | −10 | −52 | 66 |
| Posterior Cingulate Gyrus, R | 1 | 3.10 | 6 | −36 | 46 |
| Superior Parietal Lobule, R | 1 | 3.01 | 14 | −50 | 64 |
| Lateral Occipital Cortex (Sup), R | 1 | 2.91 | 24 | −58 | 52 |
aPresents the brain areas where the brain activation to correct inhibition to lures was significantly greater in the Amnestic/Non-Amnestic compared to Amnestic type groups on fMRI. bPresents the brain areas where the brain activation to correct inhibition to lures was significantly greater in the Amnestic/Non-Amnestic compared to the Unimpaired type group on fMRI. A ‘Cluster’ is a group of anatomically adjacent voxels found to be statistically significant after thresholding with z-threshold = 2.3 and p = 0.05. Z-score represents the magnitude of group differences in activation and Montreal Neurological Institute (MNI) coordinates (x, y and z axis) represent a standardized way of presenting the anatomical location of the peak Z-score on a normalized brain template.