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. 2016 Dec 6;6:38310. doi: 10.1038/srep38310

Figure 4. PLIN5 exerts a protective role against palmitate-induced lipotoxicity.

Figure 4

(A) Glycogen synthesis was measured in control myotubes (Ad-GFP) and myotubes overexpressing PLIN5 (Ad-PLIN5) using [U-14C] glucose in absence or presence of 100 nM insulin, in control cells and in cells treated with 300 μM of palmitic acid for 24 h (n = 9). (B) Total diacylglycerols (DAG) and (C) Ceramide (CER) d18:1/16:0 content were measured in control myotubes (Ad-GFP) and myotubes overexpressing PLIN5 (Ad-PLIN5) (n = 4). *p < 0.05, **p < 0.01 versus Ad-GFP.