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. 2016 Aug 26;154(2):241–252. doi: 10.1093/toxsci/kfw162

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Published by Oxford University Press on behalf of the Society of Toxicology 2016. This work is written by US Government employees and is in the public domain in the US.

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FIG. 2 — Effects of flame retardants on C. elegans feeding. A, Top left: Groups of 25 adult nematodes were exposed for 24 h to various concentrations of flame retardants, illustrated by the horizontal bars. Flame retardants are grouped as: aliphatic organophospate flame retardants (OPFRs); aromatic OPFRs; brominated flame retardants including BDEs. The organophosphate pesticide chlorpyifos and aromatic OPFR TOCP were used as positive controls. Lowest effective concentrations (LECs) [dots] and EC50s [crosses] with 95% confidence intervals are also displayed. B, Bottom left: Scatterplots of observed maximum effect size (log(EXT)) and lowest effective concentration (LEC, in log scale). The horizontal dashed line refers to the maximum effect, no feeding, for this assay. C, Top right: Sample concentration-effect plot for BPDP, a representative OPFR. D, Bottom right: Sample concentration-effect plot for DE-71, a representative PBDE.