FIG. 3.

Hepatic lipid accumulation in male mice gavaged with sesame oil vehicle or 30 µg/kg TCDD every 4 days for 28 days. (A) Representative photomicrographs of liver sections stained with Oil Red O (ORO). Scale bars represent 50 µm. (B) Quantitation of ORO staining is represented as mean + SEM for N = 4 (PAR-1^+/+vehicle), 5 (PAR-1^+/+TCDD), 3 (PAR-1^−/− vehicle) and 6 (PAR-1^−/− TCDD). Lines with an asterisks (*) above indicate a significant difference (P ≤ 0.05) within genotypes determined by 2-way ANOVA followed by Student–Newman–Keul’s post hoc test. No difference was observed between genotypes.