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. 2016 Dec 5;16:252. doi: 10.1186/s12883-016-0771-4

Table 1.

Demographic and anthropometric data on all patients, MS patients and HSP/HA patients

All MS HSP/HA
Number (%) 168 (100) 91 (54.4) 77 (45.6)
Women (%) 82 (48.8) 46 (50.5) 36 (46.8)
Disease phenotype (%) RRMS 51 (56.0)
SPMS 34 (37.4)
PPMS 6 (6.6)
HSP 61 (79.2)
HA 12 (15.6)
HSP w/ataxia 4 (5.2)
Age (SD) 55.3 (±10.4) 52.0 (±10.3) 52.7 (±10.6)
Disease duration >20 years (%) 93 (55.4) 46 (50.5)a 47(61.0)
Years since onset (SD) 24.2 (±12.8) 21.3 (±9.0)a 27.7 (±15.4)
Disability (SD)
 No aid 84 (50.0) 49 (53.8) 35 (45.5)
 One or two sticks 65 (38.7) 31 (34.1) 34 (44.2)
 In wheel chair 19 (11.3) 11 (12.1) 8 (10.4)
EDSS 4.9 (median 5.0, range: 1.5-8.0)
Height, cm (SD) 172.7 (±8.6) 173.2 (±8.3) 172.1 (±8.9)
Weight, kg (SD) 74.3 (±16.3) 71.8 (±14.1)a 77.2 (±18.2)
BMI Kg/m2 (SD) 24.8 (±4.5) 23.9 (±4.2)a 25.8 (±4.7)
Total body fat % (SD) 32.3 (±8.5) 31.6 (±8.5) 33.0 (±8.5)

Abbreviations: EDSS Expanded Disability Status Scale, RRMS relapsing remitting multiple sclerosis, SPMS secondary progressive multiple sclerosis, PPMS primary progressive multiple sclerosis, HSP hereditary spastic paraplegia, HA hereditary ataxia, BMI body mass index

a p <0.05 (independent sample t-test) compared to patients with HSP/HA