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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Circ Heart Fail. 2016 Aug;9(8):e003048. doi: 10.1161/CIRCHEARTFAILURE.116.003048

Table 2.

WHF rates according to Trial Definition

Therapy DOSE trial ROSE trial
DOSE WHF definition 72/299 (24.1%) N/A
ROSE WHF definition 15/299 (5.0%) 22/347 (6.3%)

WHF indicates worsening heart failure; ROSE, Renal Optimization Strategies; DOSE, Diuretic Optimization Strategies Evaluation; N/A, Not applicable.