Table 4. Summary on major differences between the East and West.
| East | West | |
|---|---|---|
| Risk of embolism | Lower than the Westerners. Common form is cerebrovascular variety that may lead to death or disability. |
Higher than the Easterners. Common form is cardiovascular variety including deep vein thrombosis. |
| Risk of bleeding | Higher than the Westeners due to different drug metabolism (greater body weight-normalized plasma unbound clearance of drug) and higher rate of H. pylori infection. | Lower than the Easterners. Tolerates well with low-risk endoscopic procedures during antiplatelet and/or anticoagulant medications. |
| Managing warfarin | Lower international normalized ratio value (1.6-2.6) than the Westerners are appropriate for prophylaxis of thromboembolism. | Tolerates well with low-risk procedures (endoscopic biopsy) without significant bleeding. |
| Managing aspirin | Lower dose is recommended than the Westerners due to higher risk of bleeding. | Tolerates well with few high-risk procedures (endoscopic sphincterotomy and colon polypectomy) without significant bleeding. |