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(a) High molecular weight cytokeratin is positive in the squamous cell carcinoma element. Immunostaining (AE1/3), x 200. (b) p53 expression in squamous cell carcinoma element of the esophageal tumor. Immunostaining, x 200. (c) Synaptophysin is positive in the small cell carcinoma element of the esophageal tumor cells. Immunostaining, x 200. (d) Ki-67 labeling in the small cell carcinoma element of the esophageal tumor. The labeling is 95%. Immunostaining, x 200.
