Table 1.
Input | Description | Units | Baseline | Lower | Upper |
---|---|---|---|---|---|
Pa | Mean arterial pressure | mmHg | 100 | 75 | 125 |
Partial pressure of | mmHg | 40 | 37.5 | 42.5 | |
Arterial oxygen saturation | % | 96 | 90 | 100⁎ | |
u | Demand | – | 1.0 | 0.75 | 1.25 |
Fluxy | Normalised LD flux | – | 1.0 | 0.75 | 1.25 |
Spontaneous increase in arterial saturation was deemed implausible in typical functional activation experiments, so the baseline value of 96% was used as the upper bound when optimising this parameter for the scenarios in Fig. 5.