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. 2016 Dec 6;13(12):e1002192. doi: 10.1371/journal.pmed.1002192

Table 1. Enriched biological pathways associated with prognostic lncRNAs by guilt-by-association analysis.

Good Prognosis Group Poor Prognosis Group
Pathways Number of lncRNAs Pathways Number of lncRNAs
Intracellular signaling cascade 67 Response to external stimulus 59
Protein kinase cascade 61 Chromosome organization and biogenesis 55
Response to external stimulus 60 RNA processing 54
Organ development 58 Cell cycle (GO:0007049) 53
G protein coupled receptor protein signaling pathway 56 Cell cycle process 53
Cell surface receptor linked signal transduction 56 Cell cycle phase 52
Defense response 56 Defense response 52
Signal transduction 56 Mitotic cell cycle 51
Protein amino acid phosphorylation 55 Immune response 51
Regulation of signal transduction 55 RNA metabolic process 50

lncRNA, long noncoding RNA.