Table 1. Enriched biological pathways associated with prognostic lncRNAs by guilt-by-association analysis.
Good Prognosis Group | Poor Prognosis Group | ||
---|---|---|---|
Pathways | Number of lncRNAs | Pathways | Number of lncRNAs |
Intracellular signaling cascade | 67 | Response to external stimulus | 59 |
Protein kinase cascade | 61 | Chromosome organization and biogenesis | 55 |
Response to external stimulus | 60 | RNA processing | 54 |
Organ development | 58 | Cell cycle (GO:0007049) | 53 |
G protein coupled receptor protein signaling pathway | 56 | Cell cycle process | 53 |
Cell surface receptor linked signal transduction | 56 | Cell cycle phase | 52 |
Defense response | 56 | Defense response | 52 |
Signal transduction | 56 | Mitotic cell cycle | 51 |
Protein amino acid phosphorylation | 55 | Immune response | 51 |
Regulation of signal transduction | 55 | RNA metabolic process | 50 |
lncRNA, long noncoding RNA.