Figure 1. A wire-mesh-grid device (WMGD) produced REM sleep loss during the dark period in mice.
(A) A pictorial representation of the WMGD (left) and the housing cage in which the WMGD was placed (right). (B and C) Time-courses (25–48 hr) of slow wave sleep (SWS), REM sleep and wake (B) and time spent in each sleep stage (C). Black and white bars in (B) indicate dark and light period, respectively. *p < 0.05 and **p < 0.01 indicate significant differences between baseline and WMGD exposure (n = 3).
Figure 1—figure supplement 1. REM sleep does not rebound during the light phase in mice exposed to the WMGD for 25–48 hr compared to baseline. .
REM, Rapid eye movement.