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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Contrast Media Mol Imaging. 2016 Jul 11;11(5):371–380. doi: 10.1002/cmmi.1701

Figure 3.

Figure 3

Comparison of brain uptake of no-carrier-added (NCA) and carrier-added (CA) 52Mn with ex vivo gamma counting and in vivo PET/CT. We observed higher activity uptake of NCA 52Mn in both ex vivo gamma counting measurements of the excised brain at 24 and 48 hours (A, B) as well as in vivo with PET/CT for up to 7 days following contrast delivery (C). Ex vivo measurements are the average of 3 subjects per contrast agent formulation and time point, while in vivo PET/CT was performed on one subject per contrast agent formulation in this initial comparative imaging study.