Table 2.

Bivariate and multivariable analysis of the association between HIV-associated immune suppression and treatment success among multidrug-resistant tuberculosis patients in Botswana, 2006 – 2013.

Variable	Percent with treatment success (n/N)	Bivariate analysis Risk ratio (95% confidence intervals)	Multivariable model Risk ratio (95% confidence intervals)
Sex
Female	80.0% (212/265)	1.00	1.00
Male	70.8% (228/322)	0.885 (0.807-0.971)	0.934 (0.847 - 1.031)
Age in years
15 - 24	83.3% (70/84)	1.00
25 - 34	77.1% (121/157)	0.925 (0.814-1.051)
35 – 44	76.0% (127/167)	0.913 (0.803-1.037)
45 – 54	69.0% (80/116)	0.828 (0.709-0.966)
≥55	67.9% (36/53)	0.815 (0.662-1.004)
Age (+10 year)			0.945 (0.907 - 0.985)
Prior TB
No	92.0% (23/25)	1.00	1.00
Yes	74.2% (418/563)	0.807 (0.712-0.915)	0.895 (0.772 - 1.037)
CD4+ T cell count, cells/mm3*
HIV-uninfected	79.4% (143/180)	1.00	1.00
<100	64.6% (31/48)	0.813 (0.651-1.015)	0.835 (0.667 - 1.046)
100 – 199	70.3% (45/64)	0.885 (0.742-1.055)	0.958 (0.810 - 1.133)
200 – 349	80.5% (62/77)	1.014 (0.888-1.157)	1.021 (0.896 - 1.164)
≥350	85.9% (67/78)	1.081 (0.962-1.215)	1.077 (0.963 - 1.205)

^*Patients with unknown CD4+ T cell counts (n = 141) were excluded from the analysis.