. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: Liver Int. 2016 Jul 6;37(1):80–89. doi: 10.1111/liv.13183

Table 1.

Multivariate Cox regression analysis demonstrating that LPL expression is an independent predictor of survival in HCC patients.

Covariates	Each covariate separately (HR and 95% CI)	Full model (HR and 95% CI)	Stepwise backward (HR and 95% CI)

Age	1.005 (0.970–1.041)	0.776 (0.414–1.456)	–

Male sex	1.017 (0.515–2.011)	1.199 (0.501–2.867)	–

Cirrhosis (y/n)	0.858 (0.438–1.682)	0.864 (0.411–1.813)	0.429 (0.198–0.932)^*

Etiology
HCV	Reference	Reference	Reference
HBV	0.816 (0.429–1.553)	1.095 (0.493–2.431)	1.253 (0.630–2.492)
Ethanol	0.648 (0.245–1.714)	1.153 (0.384–3.462)	1.297 (0.443–3.798)
Wilson's disease	0.409 (0.054–3.122)	0.017 (0.001–0.256)^*	0.035 (0.004–0.346)^*

Diameter > 3 cm	1.446 (0.729–2.869)	1.239 (0.600–2.561)	–

AFP > 300 ng/ml	1.514 (0.813–2.820)	1.193 (0.570–2.498)	–

Edm-Ste			–
II	Reference
III	1.053 (0.513–2.159)
IV	2.084 (0.929–4.675)

LPL > 0.10566	4.853 (2.491–9.453)^**	5.901 (2.668–13.050)^**	12.301 (4.868–31.084)^**

p<0.05

^**

p<0.0001