Table.
Previously Reported Cases of ADEM Occurring after HPV Vaccination.
| Reference No. | Number of cases |
Vaccine | Intervals after last injection |
Progress to multiple sclerosis |
Treatment | Prognosis |
|---|---|---|---|---|---|---|
| 6 | 4 | Gardasil | 3-6 months | NMOSD | IVMP, Rituximab | Good |
| 16 | 1 | Gardasil | 4 weeks | None | IVMP, IVCY | Good |
| 17 | 5 | Gardasil | ~3 weeks | 3 | IVMP | Good |
| 18 | 1 | Gardasil | 10 days | None | IVMP | Good |
| 19 | 2 | Gardasil | 4 weeks | 2 | IVMP | Good |
| Current cases | 2 | Gardasil/ Cervarix |
~2 weeks | None | IVMP/no treatment | Good |
NMOSD: neuromyelitis optica spectrum disorder, IVMP: intravenous methyl prednisolone, IVCY: intravenous cyclophosphamide