Table 4. Receptor specificity of H6 viruses with TRBC and α2,3-sialidase-treated TRBCs.
Virus | HA titers with untreated 1% TRBC (HAU/50 μL) | HA titersa with sialidase-treated 1% TRBC (HAU/50 μL) | Receptor specificity |
---|---|---|---|
EV/JX/24/09 | 64 | Neg | α2,3-SA binding |
EV/JX/25/09 | 32 | 8 | α2,3-SA and α2,6-SA binding |
EV/HN/1/09 | 256 | Neg | α2,3-SA binding |
EV/HB-JZ/02/10 | 128 | 32 | α2,3-SA and α2,6-SA binding |
EV/HN/2/10 | 64 | Neg | α2,3-SA binding |
EV/HN/03/10 | 64 | Neg | α2,3-SA binding |
EV/HN/07/10 | 16 | Neg | α2,3-SA binding |
EV/JX/15/10 | 64 | 64 | α2,3-SA and α2,6-SA binding |
EV/HN/11/10 | 32 | Neg | α2,3-SA binding |
EV/HN/14/10 | 32 | Neg | α2,3-SA binding |
EV/GX/02/10 | 16 | Neg | α2,3-SA binding |
EV/JX/17/11 | 32 | 8 | α2,3-SA and α2,6-SA binding |
EV/JX/19/11 | 64 | 16 | α2,3-SA and α2,6-SA binding |
EV/HN/18/11 | 32 | Neg | α2,3-SA binding |
EV/HN/19/11 | 32 | Neg | α2,3-SA binding |
EV/HN/20/11 | 32 | Neg | α2,3-SA binding |
RG-A/anhui/1/05b | 512 | Neg | α2,3-SA binding |
A/CA/04/09b | 64 | 64 | α2,6-SA binding |
Neg: no HA titer, negative.
The full names and subtypes of the viruses are described in ‘Materials and Methods' section.