Table 2.
Comparison of serum Total Oxidant Status, Total Antioxidant Status, and Oxidative Status Index in patients undergoing cardiac surgery with cardiopulmonary bypass circuit coated with phosphorylcholine Group I versus noncoated Group II at different time points.
| T0 | T1 | T2 | T3 | T4 | ||
|---|---|---|---|---|---|---|
| TAS (mmoL of trolox/L, mean ± SD) | Group I (n = 18) | 0.55 ± 0.12 | 0.81 ± 0.2 | 0.81 ± 0.3 | 0.7 ± 0.23 | 0.88 ± 0.2 |
| Group II (n = 14) | 0.45 ± 0.17 | 0.48 ± 0.13 | 0.5 ± 0.16 | 0.43 ± 0.13 | 0.53 ± 0.18 | |
| p ∗ | 0.084 | 0.003 | 0.001 | 0.002 | 0.001 | |
|
| ||||||
| TOS (mean μmol H2O2/L ± SD) | Group I (n = 18) | 6.24 ± 1.93 | 12.5 ± 6.18 | 12.96 ± 6.34 | 11.73 ± 6.71 | 15.29 ± 11.71 |
| Group II (n = 14) | 5.77 ± 1.3 | 4.57 ± 1.76 | 4.85 ± 1.90 | 4.01 ± 1.55 | 3.14 ± 1.16 | |
| p ∗ | 0.621 | 0.001 | 0.001 | 0.003 | 0.001 | |
|
| ||||||
| OSI (mean ± SD) | Group I (n = 18) | 12.1 ± 5.45 | 17.11 ± 10.83 | 19.09 ± 12.51 | 21.09 ± 17.23 | 18.01 ± 14.23 |
| Group II (n = 14) | 14.13 ± 4.79 | 10.09 ± 4.76 | 11 ± 5.55 | 10.29 ± 5.49 | 6.87 ± 4.05 | |
| p ∗ | 0.160 | 0.119 | 0.063 | 0.102 | 0.048 | |
Continuous data were reported as mean ± standard deviation (SD) if normally distributed, as indicated by the shape of the distribution pattern in the Shapiro-Wilk test.
∗ p values for comparisons between Group I and Group II with Mann–Whitney U test. A p value of <0.05 is statistically significant. OSI: Oxidative Stress Index, TAS: Total Antioxidant Status, and TOS: Total Oxidant Status.