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. 2016 Nov 29;7:13375. doi: 10.1038/ncomms13375

Figure 4. Distinct hippocampal-prefrontal functional pathways after consolidation.

Figure 4

(a) The left hippocampal seed (MNI, peak at −33, −33 and −6) used in gPPI analysis of task-based functional connectivity during memory suppression. (b,d) Increased hippocampal functional connectivity with the left and right DLPFC was positively associated with more effective suppression for newly acquired memories (cluster in hot), but not after overnight consolidation. (c,e) Attenuated hippocampal functional connectivity with the left DLPFC was predictive of more effective suppression of overnight consolidated memories (cluster in blue), but not for newly acquired ones. Dotted lines indicate 95% confidence intervals and solid line indicates the best linear fit. MNI, Montreal Neurological Institute coordinate system.