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. 2016 Jun 10;6(6):e434. doi: 10.1038/bcj.2016.41

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Copyright © 2016 Macmillan Publishers Limited

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Differential gene expression profiling between B-cells from Eμ-TCL1 and Eμ-TCL1;p53^R172H/+ mice. (a) Heat map of hierarchical clustering of gene expression profiles between B-cells from Eμ-TCL1 and Eμ-TCL1;p53^R172H/+ mice. (b) Gene set enrichment analysis enrichment plots of differentially expressed gene sets from B-cells isolated from Eμ-TCL1 and Eμ-TCL1;p53^R172H/+ mice. Reactome Meiotic Recombination, normalized enrichment score (NES)=2.39 and false-discovery rate (FDR)=0.075; Amundsom Gamma Radiation Response, NES=2.014 and FDR=0.198; Kong E2F3, NES=1.99 and FDR=0.192; and Whitefield Cell Cycle Literature, NES=1.97, FDR=0.200. (c) KEGG-pathway analyses of differentially regulated biological pathways in B-cells from Eμ-TCL1 and Eμ-TCL1;p53^R172H/+ mice.