Table 3.
Insulin resistance associated loci based on genome wide association studies
| Chr1 | Genes2 |
|---|---|
| 1p | NOTCH2 |
| ADAM30 | |
| SLC44A3 | |
| 1q | PCNXL2 |
| CR2 | |
| F3 | |
| 2p | BCL11A |
| THADA | |
| 2q | IRS1 |
| GRB14 | |
| G6PC2-ABCB11 | |
| RBM43 | |
| RND3 | |
| RBMS1 | |
| ITGB6 | |
| 3p | SYN2 |
| PPARG | |
| ADAMTS9 | |
| PSMD6 | |
| 3q | ST6GAL1 |
| ZPLD1 | |
| PLS1 | |
| IGF2BP2 | |
| PEX5L | |
| 4p | WFS1 |
| PPP2R2C | |
| MAEA | |
| 5q | CETN3 |
| ZBED3 | |
| 6p | KCNK16 |
| CDKAL1 | |
| ZFAND3 | |
| VEGFA | |
| 7p | DGKB |
| AGMO | |
| GCC1 | |
| JAZF1 | |
| 7q | PAX4 |
| ACHE | |
| KLF14 | |
| 8q | SLC30A8 |
| TP53INP1 | |
| 9p | PTPRD |
| CDKN2A | |
| CDKN2B | |
| GLIS3 | |
| 9q | CHCHD2P9 |
| 10p | CDC123 |
| CAMK1D | |
| 10q | TCERG1L |
| PANK1 | |
| HHEX | |
| VPS26A | |
| KIF11 | |
| TCF7L2 | |
| 11p | KCNQ1 |
| GALNT18 | |
| KCNJ11 | |
| 11q | MTNR1B |
| ARAP1 | |
| TMEM45B | |
| BARX2 | |
| 12q | DCD |
| HMGA2 | |
| HNF1A | |
| TSPAN8 | |
| LGR5 | |
| 13q | SPRY2 |
| 14q | C14orf70 |
| 15q | ZFAND6 |
| C2CD4B | |
| AP3S2 | |
| C2CD4A | |
| C2CD4B | |
| HMG20A | |
| PRC1 | |
| 16q | CMIP |
| WWOX | |
| FTO | |
| 17p | SRR |
| 17q | HNF1B |
| 18p | LPIN2 |
| 19q | PEPD |
| ACP7 | |
| 20q | HNF4A |
| 21q | HUNK |
| Xq | DUSP9 |
1
Chromosome number
2
Nearest genes to loci identified in association with insulin resistance