Table 4.
Hypertriglyceridemia associated loci based on GWAS studies
| Chr1 | Nearest genes2 | Gene name |
|---|---|---|
| 1p | ANGPTL3 | Angiopoietin- like 3 |
| DOCK7 | Dedicator of cytokinesis 7 | |
| ATG4C | Autophagy related 4C, cysteine peptidase | |
| 1q | GALNT2 | Polypeptide N-acetylgalactosaminyltransferase 2 |
| 2p | GCKR | Glucokinase (hexokinase 4) regulator |
| APOB | Apolipoprotein B | |
| 7q | BAZ1B | Bromodomain adjacent to zinc finger domain 1B |
| BCL7B | B-cell CLL/lymphoma 7B | |
| TBL2 | Transducin (beta)-like 2; MLX interacting protein-like | |
| MLXIPL | ||
| 8p | LPL/SLC18A1 | Lipoprotein lipase; Solute carrier family 18A1 |
| XKR6 | XK Kell blood group complex subunit-related 6 | |
| SLC35G5 | Solute carrier family 35, member G5 | |
| TRIB1 | Tribbles pseudokinase 1 | |
| 11q | FADS1-FADS2-FADS3 | Fatty acid desaturase 1, 2 and 3 |
| APOA1-C3-A4-A5 | Apolipoprotein A1-C3-A4-A5 | |
| ZNF259, BUD13 | Zinc finger protein 259; BUD13 homolog | |
| 15q | RASGRP1 | RAS guanyl releasing protein 1 |
| 19p | NCAN, SUGP1 | Neurocan; SURP and G patch domain containing 1 |
| CILP2 | Cartilage intermediate layer protein 2 | |
| PBX4 | Pre-B-cell leukemia homeobox 4 | |
| 19q | TOMM40 | Translocase of outer mitochondrial membrane 40 homolog; |
| APOE-C1-C2 | Apolipoprotein E; Apolipoprotein C-I | |
| 20q | PLTP | Phospholipid transfer protein |
1
Chromosome number
2
Nearest genes to hypertriglyceridemia associated loci