Table 5.
Genes associated with blood high density lipoprotein levels based on genome wide association studies
| Chr1 | Nearest genes2 | Gene name |
|---|---|---|
| 1q | GALNT2 | Polypeptide N-acetylgalactosaminyl transferase 2 |
| 2p | APOB | Apolipoprotein B |
| 8p | LPL, SLC18A1 | Lipoprotein lipase, solute carrier family 18A1 |
| 9p | TTC39B | Tetratricopeptide repeat domain 39B |
| 9q | GRIN3A | Glutamate receptor ionotropic N-methyl-D-aspartate 3A |
| PPP3R2 | Protein phosphatase 3 regulatory subunit B beta | |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1) | |
| 11p | MADD | MAP-kinase activating death domain |
| NR1H3 | Nuclear receptor subfamily 1 group H member 3 | |
| 11q | FADS1-FADS2-FADS3 | Fatty acid desaturase 1, 2 and 3 |
| APOA1-C3-A4-A5, ZNF259 | Apolipoprotein A1-C3-A4-A5; Zinc finger protein 259; | |
| BUD13 | BUD13 homolog | |
| 15q | LIPC | Lipase hepatic |
| 16q | CETP | Cholesteryl ester transfer protein, plasma |
| LCAT | Lecithin-cholesterol acyltransferase | |
| CTCF | CCCTC-binding factor (zinc finger protein) | |
| 17p | METTL16 | Methyltransferase like 16; |
| PAFAH1B1 | Platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 | |
| 18q | LIPG, ACAA2 | Lipase endothelial; Acetyl-CoA acyltransferase 2 |
| 19p | ANGPTL4 | Angiopoietin- like 4 |
| 20q | HNF4A | Hepatocyte nuclear factor 4, alpha |
| PLTP | Phospholipid transfer protein |
Chromosome number
Genes nearest to identified loci that are associated with high density lipoprotein (HDL) levels in the blood