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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Curr Opin Lipidol. 2016 Apr;27(2):162–171. doi: 10.1097/MOL.0000000000000276

Table 5.

Genes associated with blood high density lipoprotein levels based on genome wide association studies

Chr1 Nearest genes2 Gene name
1q GALNT2 Polypeptide N-acetylgalactosaminyl transferase 2
2p APOB Apolipoprotein B
8p LPL, SLC18A1 Lipoprotein lipase, solute carrier family 18A1
9p TTC39B Tetratricopeptide repeat domain 39B
9q GRIN3A Glutamate receptor ionotropic N-methyl-D-aspartate 3A
PPP3R2 Protein phosphatase 3 regulatory subunit B beta
ABCA1 ATP-binding cassette, sub-family A (ABC1)
11p MADD MAP-kinase activating death domain
NR1H3 Nuclear receptor subfamily 1 group H member 3
11q FADS1-FADS2-FADS3 Fatty acid desaturase 1, 2 and 3
APOA1-C3-A4-A5, ZNF259 Apolipoprotein A1-C3-A4-A5; Zinc finger protein 259;
BUD13 BUD13 homolog
15q LIPC Lipase hepatic
16q CETP Cholesteryl ester transfer protein, plasma
LCAT Lecithin-cholesterol acyltransferase
CTCF CCCTC-binding factor (zinc finger protein)
17p METTL16 Methyltransferase like 16;
PAFAH1B1 Platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
18q LIPG, ACAA2 Lipase endothelial; Acetyl-CoA acyltransferase 2
19p ANGPTL4 Angiopoietin- like 4
20q HNF4A Hepatocyte nuclear factor 4, alpha
PLTP Phospholipid transfer protein
1

Chromosome number

2

Genes nearest to identified loci that are associated with high density lipoprotein (HDL) levels in the blood