Table 1.
Clinical and laboratory features of MetS and control population in Romanians. Data are presented as mean ± SEM and controls and MetS groups were compared by using Mann-Whitney test for numerical variable and chi2 for nominal variable
| CTR | MetS | P value* | |
|---|---|---|---|
| n | 42 | 63 | NA |
| Gender (F/ M) | 31/ 11 | 51/ 12 | NA |
| Age (years) | 47.9 ± 1.7 | 50.9 ± 1.4 | NS |
| BMI (kg/ m2) | 22.8 ± 0.4 | 35.7 ± 0.8 | <0.0001 |
| Waist (cm) | 81.8 ± 1.2 | 110.7 ± 1.8 | <0.0001 |
| Obesity (%)† | 2.3 | 85.7 | <0.0001 |
| SBP (mmHg) | 117.1 ± 2.0 | 145.0 ± 2.6 | <0.0001 |
| DBP (mmHg) | 73.2 ± 1.4 | 87.6 ± 2.1 | <0.0001 |
| Hypertension (%)‡ | 26.1 | 93.6 | <0.0001 |
| Fasting Glucose (mmol/ L) | 4.7 ± 0.0 | 6.8 ± 0.2 | <0.0001 |
| Fasting insulin (µU/mL) | 5.4 ± 0.4 | 16.5 ± 1.4 | <0.0001 |
| Hyperglycemia (%)c | 0.0 | 79.3 | <0.0001 |
| HOMA IR | 1.1 ± 0.8 | 4.9 ± 0.4 | <0.0001 |
| Insulin resistance (%)§ | 9.5 | 88.8 | <0.0001 |
| Triglycerides (mmol/ L) | 0.9 ± 0.0 | 1.9 ± 0.1 | <0.0001 |
| HDL-cholesterol (mmol/ L) | 0.7 ± 0.0 | 0.5 ± 0.0 | <0.0001 |
| High Triglycerides (%)c | 19.0 | 85.7 | <0.0001 |
| Low HDL (%)c | 9.5 | 44.4 | <0.0001 |
| CRP (mg/ dL) | 0.2 ± 0.0 | 1.6 ± 0.5 | NS |
| Copeptin (ng/ mL) | 0.42 ± 0.0 | 0.6 ± 0.0 | 0.004 |
| Smokers (%) | 19.5 | 22.0 | NS |
| *NA stands for non applicable, NS stands for non significant; †Obesity was considered by BMI and waist circumference calculated separately between men and women; ‡hyperglycemia, high triglycerides and low HDL were considered taking into account treatment or pre-diagnosed type 2 diabetes; §insulin resistance was considered as function of HOMAIR values with a cut-off of 1.7. |